In unseren News haben wir schon des öfteren über eine neue pathologische Entität, die s.g. IgG4-assoziierten Erkrankungen gesprochen (Tabelle 1)
Fast alle dieser Erkrankungen sind mit der Entwicklung fibrotischer Komplikationen vergesellschaftet. Man sollte bei fibrotischen Erkrankungen daher immer auch an IgG4-Related Disease denken.
IgG4-RD accounts for some or all of the cases
Known previously by the following names:
→Mikulicz’s disease
→Küttner’s tumor
→Riedel’s thyroiditis
→Eosinophilic angiocentric fibroses
→Multifocal fibrosclerosis
→Lymphoplasmacytic sclerosing pancreatitis/autoimmune pancreatitis
→Inflammatory pseudotumor
→Fibrosing mediastinitis
→Sclerosing mesenteritis
→Retroperitoneal fibroses (Ormond’s disease)
→Periaortitis/periarteritis
→Inflammatory aortic aneurysm
→Cutaneous pseudolymphoma
→Idiopathic hypertrophic pachymeningitis
→Idiopathic tubulointerstitial nephritis
→Idiopathic hypocomplementemic tubulointerstitial nephritis
with extensive tubulointerstitial deposits
→Membranous glomerulonephritis
→Idiopathic cervical (paravertebral) fibrosis
Known previously by the following names:
→Mikulicz’s disease
→Küttner’s tumor
→Riedel’s thyroiditis
→Eosinophilic angiocentric fibroses
→Multifocal fibrosclerosis
→Lymphoplasmacytic sclerosing pancreatitis/autoimmune pancreatitis
→Inflammatory pseudotumor
→Fibrosing mediastinitis
→Sclerosing mesenteritis
→Retroperitoneal fibroses (Ormond’s disease)
→Periaortitis/periarteritis
→Inflammatory aortic aneurysm
→Cutaneous pseudolymphoma
→Idiopathic hypertrophic pachymeningitis
→Idiopathic tubulointerstitial nephritis
→Idiopathic hypocomplementemic tubulointerstitial nephritis
with extensive tubulointerstitial deposits
→Membranous glomerulonephritis
→Idiopathic cervical (paravertebral) fibrosis
Ref.:
E. Atac et al.
A Spotlight on IgG4-Related Disease
The Rheumatologist 1/2013